FIND® (Fragment INduced Diversity) is a rapid in vitro evolution technology that mimics the natural process of creating protein diversity through recombination. FIND® is the only evolution technology based on single-stranded DNA and the power of FIND® is its ability to generate myriads of antibody and protein variants, from which the perfect variant can be selected.
Key technological benefits of FIND®
- Accumulation of beneficial mutations and filtering out unwanted mutations
- Multiple properties can be optimized
- No prior information on protein structure, mechanism, active site, epitopes or binding sites needed
- Mutations can be directed to specific regions
- Eligible for a range of proteins (e.g. therapeutic protein, mAbs, vaccines, enzymes, scaffolds, cytokines etc.)